madmanxpilot 880 Posted January 26 Share Posted January 26 This makes interesting reading. Lots of hot topics covered by the Astra Zeneca CEO. https://www.repubblica.it/cronaca/2021/01/26/news/interview_pascal_soriot_ceo_astrazeneca_coronavirus_covid_vaccines-284349628/amp/?__twitter_impression=true 1 Quote Link to post Share on other sites
Neil Down 8,016 Posted January 26 Share Posted January 26 2 hours ago, Non-Believer said: Ashford says the cost of the airport "vaccination hub" will be released and "won't be a secret". He didn't say when though. He can feck off if he thinks I'm waiting 10 years for that release... 1 Quote Link to post Share on other sites
Banker 2,008 Posted January 26 Author Share Posted January 26 1 hour ago, Neil Down said: He can feck off if he thinks I'm waiting 10 years for that release... It will be commercially sensitive Quote Link to post Share on other sites
dilligaf 9,448 Posted January 26 Share Posted January 26 2 hours ago, Neil Down said: He can feck off if he thinks I'm waiting 10 years for that release... Have you been in hiding ? Quote Link to post Share on other sites
Newbie 277 Posted January 27 Share Posted January 27 12 hours ago, madmanxpilot said: This makes interesting reading. Lots of hot topics covered by the Astra Zeneca CEO. https://www.repubblica.it/cronaca/2021/01/26/news/interview_pascal_soriot_ceo_astrazeneca_coronavirus_covid_vaccines-284349628/amp/?__twitter_impression=true Interesting that he says he thinks the one dose strategy followed by the UK is the right way to go, at least for the AZ vaccine. Quote Link to post Share on other sites
piebaps 3,822 Posted January 27 Share Posted January 27 I for one don't want to see Ashie's big release. 3 1 Quote Link to post Share on other sites
madmanxpilot 880 Posted January 27 Share Posted January 27 2 hours ago, Newbie said: Interesting that he says he thinks the one dose strategy followed by the UK is the right way to go, at least for the AZ vaccine. Indeed. Oxford/AZ have said that there is a 'sweet spot' for administering the second dose between eight and twelve weeks. This may explain why the half dose/full dose regimen showed greater efficacy as this sub group had their doses administered at a greater interval. As this is the case, I'm unsure why they haven't changed the recommended dosing schedule with the regulators. Prof Wei Shen Lim, the chair of the Covid-19 immunisation group of the JCVI, told MPs further analysis by AstraZeneca showed the improved protection came from spacing out the doses. “People who had the half dose then full dose were those who were vaccinated at a longer time interval, roughly six to 12 weeks, and what they’ve seen in their data is that people who have the second dose later probably have a three times higher antibody level than those who were vaccinated earlier. So if anything, it suggests that increasing the dose interval is beneficial,” he said. Sir Mene Pangalos, the executive vice-president of biopharmaceuticals research and development at AstraZeneca, told the committee the first vaccine shot was more protective over time. “What we’re seeing with our data so far is that as you go to the eight- to 12-week interval, you actually increase vaccine efficacy. People are protected enough with the first dose, to around 70%, but we see that within that eight- to 12-week interval is actually the sweet spot,” he said. Quote Link to post Share on other sites
Banker 2,008 Posted January 27 Author Share Posted January 27 36 minutes ago, madmanxpilot said: Indeed. Oxford/AZ have said that there is a 'sweet spot' for administering the second dose between eight and twelve weeks. This may explain why the half dose/full dose regimen showed greater efficacy as this sub group had their doses administered at a greater interval. As this is the case, I'm unsure why they haven't changed the recommended dosing schedule with the regulators. Prof Wei Shen Lim, the chair of the Covid-19 immunisation group of the JCVI, told MPs further analysis by AstraZeneca showed the improved protection came from spacing out the doses. “People who had the half dose then full dose were those who were vaccinated at a longer time interval, roughly six to 12 weeks, and what they’ve seen in their data is that people who have the second dose later probably have a three times higher antibody level than those who were vaccinated earlier. So if anything, it suggests that increasing the dose interval is beneficial,” he said. Sir Mene Pangalos, the executive vice-president of biopharmaceuticals research and development at AstraZeneca, told the committee the first vaccine shot was more protective over time. “What we’re seeing with our data so far is that as you go to the eight- to 12-week interval, you actually increase vaccine efficacy. People are protected enough with the first dose, to around 70%, but we see that within that eight- to 12-week interval is actually the sweet spot,” he said. Don’t worry, Ashie has decided our doses!! 1 Quote Link to post Share on other sites
madmanxpilot 880 Posted January 27 Share Posted January 27 (edited) 52 minutes ago, Banker said: Don’t worry, Ashie has decided our doses!! It was quite revealing when at one of the briefings last week he spent quite a while explaining how the IOM's clinicians had debated whether to extend the period between doses, and it was a consensus of opinion that led to the adherence of the 3 or 4 week gap. This despite him, on several occasions, saying that they had a legal obligation to comply with the dosing regime specified in the approval. He has uttered many other specious comments that don't stand up to scrutiny. He was adamant that the vaccination appointments for the over 80s were not being done in alphabetical order - yet when the 111 operator was speaking to my parents when they were making their appointment last week, she said they had been done that way. I struggle to believe anything they say when it comes to technical matters. As Fauci said last week, 'if you don't know the answer, don't guess' - I think our leadership team could do with taking a leaf out of the good doctor's book. Edited January 27 by madmanxpilot 8 5 Quote Link to post Share on other sites
Banker 2,008 Posted January 27 Author Share Posted January 27 16 minutes ago, madmanxpilot said: It was quite revealing when at one of the briefings last week he spent quite a while explaining how the IOM's clinicians had debated whether to extend the period between doses, and it was a consensus of opinion that led to the adherence of the 3 or 4 week gap. This despite him, on several occasions, saying that they had a legal obligation to comply with the dosing regime specified in the approval. He has uttered many other specious comments too that don't stand up to scrutiny. He was adamant that the vaccination appointments for the over 80s were not being done in alphabetical order - yet when the 111 operator was speaking to my parents when they were making their appointment last week, she said they had been done that way. I struggle to believe anything they say when it comes to technical matters. As Fauci said last week, 'if you don't know the answer, don't guess' - I think our leadership team could do with taking a leaf out of the good doctor's book. Over 80s definitely in alphabetical order as my mum told the same, also no coordination as to where’s best to send them ie Ramsey people to airport, Colby to Douglas. He never answered questions as to why so few over 80s were vaccinated in first run of c4000 . 3 Quote Link to post Share on other sites
madmanxpilot 880 Posted January 27 Share Posted January 27 (edited) 20 minutes ago, Banker said: Over 80s definitely in alphabetical order as my mum told the same, also no coordination as to where’s best to send them ie Ramsey people to airport, Colby to Douglas. He never answered questions as to why so few over 80s were vaccinated in first run of c4000 . If you look at the 'phase one cohorts' subsection of the vaccine dashboard that was made available recently https://covid19.gov.im/vacstats, only the over 80s, those resident or working within care homes or those working in healthcare have been vaccinated so far. These people represent the first two groups of the priority list. From that, I would deduce that there are far more workers in those two groups than over 80s. Edited January 27 by madmanxpilot Quote Link to post Share on other sites
Roger Mexico 10,698 Posted January 27 Share Posted January 27 It's a fun website to play about with and they've improved it even since yesterday[1]. But there were 4397 people aged 80+ in the last Census (2106) a number I suspect will only have increased. But vaccinations for only 121 care home residents and 493 others in this group have currently given (I don't think any will have had their second dose yet). So it's because they have prioritised staff rather than because there aren't the over-80s to be vaccinated. [1] Presumably someone pointed out that, fashionable though pastel shades are, white lettering on them isn't exactly readable. It would nice to get rid of the US date formats though. 1 2 Quote Link to post Share on other sites
Southernman 16 Posted January 27 Share Posted January 27 5,365 vaccinations so far of which 724 were for over 80s. Quote Link to post Share on other sites
Nellie 639 Posted January 28 Share Posted January 28 Airport hub up and running, but by 11.00am around 30 mins behind schedule and around 50-60 elderly folk constantly outside, in the queue to be allowed into the building. Not an auspicious start! Quote Link to post Share on other sites
Happier diner 818 Posted January 28 Share Posted January 28 And some good news. No anticipation of reduced supply of AZ vaccine https://www.bbc.co.uk/news/uk-55838272 Quote Link to post Share on other sites
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